SrasV1, France, Analysis, bibRecord, 000275

International research networks in viral structural proteomics : Again, lessons from SARS

Identifieur interne : 000275 ( France/Analysis ); précédent : 000274; suivant : 000276

International research networks in viral structural proteomics : Again, lessons from SARS

Auteurs : Bruno Canard [France] ; Jeremiah S. Joseph [États-Unis] ; Peter Kuhn [États-Unis]

Source :

Antiviral research [ 0166-3542 ] ; 2008.

RBID : Pascal:08-0296266

Descripteurs français

KwdFr :
- Coopération internationale, Humains, Maladies transmissibles émergentes (virologie), Modèles moléculaires, Protéines virales (), Protéines virales (métabolisme), Protéomique (tendances), Recherche (tendances), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (), Virus du SRAS (génétique), Virus du SRAS (métabolisme).
MESH :
- génétique : Virus du SRAS.
- métabolisme : Protéines virales, Virus du SRAS.
- tendances : Protéomique, Recherche.
- virologie : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
Pascal (Inist)
- Coopération internationale, Humains, Modèles moléculaires, Protéines virales, Réseau international, Protéomique, Relation structure activité, Syndrome respiratoire aigu sévère, Virus du SRAS, Virus syndrome respiratoire aigu sévère, Génomique, Virus à ARN, Recherche et développement, Antiviral, Projet Vizier.
Wicri :
- topic : Recherche et développement.

English descriptors

KwdEn :
- Antiviral, Communicable Diseases, Emerging (virology), Genomics, Humans, International Cooperation, International network, Models, Molecular, Proteomics, Proteomics (trends), RNA virus, Research (trends), Research and development, SARS Virus (chemistry), SARS Virus (genetics), SARS Virus (metabolism), Severe Acute Respiratory Syndrome (virology), Severe acute respiratory syndrome, Severe acute respiratory syndrome virus, Structure activity relation, Viral Proteins (chemistry), Viral Proteins (metabolism).
MESH :
- chemical , chemistry : Viral Proteins.
- chemistry : SARS Virus.
- genetics : SARS Virus.
- metabolism : SARS Virus, Viral Proteins.
- trends : Proteomics, Research.
- virology : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- Humans, International Cooperation, Models, Molecular.

Abstract

Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.

Affiliations:

Links to Exploration step

Pascal:08-0296266

Le document en format XML

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<term>Relation structure activité</term>
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<front><div type="abstract" xml:lang="en">Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.</div>
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International research networks in viral structural proteomics : Again, lessons from SARS

International research networks in viral structural proteomics : Again, lessons from SARS

Source :

Descripteurs français

English descriptors

Abstract

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Links to Exploration step

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